Managing toxicities of Bruton tyrosine kinase inhibitors
https://ashpublications.org/hematology/article/2020/1/336/474309/Managing-toxicities-of-Bruton-tyrosine-kinase
WEBDec 4, 2020 · With 8 years of follow-up data since its initial pivotal study, 3 the long-term toxicity profile of ibrutinib (a first-in-class, irreversible inhibitor of BTK) is well characterized. It includes cardiac arrhythmias, bleeding, infection, diarrhea, arthralgias, and hypertension. 4-8 Acalabrutinib, the initial second-generation BTKi to earn approval from the US Food and …
DA: 94 PA: 17 MOZ Rank: 95