Adapalene (Differin) vs Tretinoin: Which is More Effective ...
Adapalene. Approved by the FDA in 1996, adapalene is a relatively new, third-generation retinoid that’s sold as both a prescription medicine and in a lower concentration as an over-the-counter gel for acne prevention and treatment.. Like tretinoin, adapalene is a retinoid. However, it has several characteristics that make it quite a unique medication when compared to tretinoin.
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