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What is a normal albumin creatinine ratio in urine?

In random urine specimens, normal urinary albumin excretion is below 17 mg/g creatinine for males and below 25 mg/g creatinine for females. Microalbuminuria is defined as an albumin:creatinine ratio of 17 to 299 for males and 25 to 299 for females. A ratio of albumin:creatinine of 300 or higher is indicative of overt proteinuria.

What is the albumin creatinine ratio (ACR)?

The Albumin Creatinine Ratio is the method employed to detect small amounts of albumin (protein) in the urine. Proteinuria and microalbuminuria are both signs of renal impairment and considered risk factors for cardiovascular morbidity and mortality. Its measurement is also part of diagnosis, staging and monitoring of chronic kidney disease (CKD).

How is albumin-to-creatinine ratio calculated?

Albumin-to-creatinine ratio is the first method of preference to detect elevated protein and is calculated by dividing albumin concentration in milligrams by creatinine concentration in grams. The normal urine ACR in young adults is less than 10 mg/g.

What does high creatinine and microalbuminuria mean?

When there is a high ACR, that is, around 35 - 300 mg/g of creatinine, it is known as microalbuminuria. This means that there is a small amount of albumin in the urine, which indicates that the kidneys may be slightly diseased.


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