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Frequently Asked Questions

What does high anti-DNA(ds) level indicate?

A high level of anti-dsDNA in the blood is strongly associated with lupus and is often significantly increased during or just prior to a flare-up. When the anti-dsDNA is positive and the person tested has other clinical signs and symptoms associated with lupus, it means that the person tested likely has lupus.

What is the normal range of antibodies?

Normal values are as follows: TPO antibody: The measured serum level should be less than 9 IU/mL. Anti-Tg antibody: The measured serum level should be less than 4 IU/mL. Thyroid-stimulating immunoglobulin antibody (TSI): This value should be less than 1.75 IU/L.

What are double stranded antibodies?

Anti-double stranded DNA (Anti-dsDNA) antibodies are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories.

What are double stranded DNA antibodies?

Anti-double stranded DNA antibody (anti-dsDNA) is one of a group of autoantibodies called antinuclear antibodies (ANA). Normally, antibodies protect against infection, but autoantibodies are produced when a person's immune system fails to adequately distinguish between "self" and "non-self."


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