WebJan 24, 2023 · Overview. Castleman disease is a rare disorder that involves an overgrowth of cells in your body's lymph nodes. The most common form of the disorder affects a single lymph node, usually in the chest or abdomen. This form is called unicentric Castleman disease.
WebCastleman disease (CD) describes a group of rare lymphoproliferative disorders that involve enlarged lymph nodes, and a broad range of inflammatory symptoms and laboratory abnormalities. Whether Castleman disease should be considered an autoimmune disease, cancer, or infectious disease is currently unknown.
WebOverview. Lymphatic system. What is Castleman disease? Castleman disease refers to a group of rare disorders that involve a hyperactive immune system. In people who are healthy, their immune system activates to fight off invaders like bacteria or viruses but then settles back down, watching and waiting for the next time it’s needed.
WebApr 27, 2023 · Castleman disease is a lymphoproliferative disorder with a nondefinite etiology and can be classified into subtypes based on clinical and histological manifestations. Therefore, this condition's high morbidity and complications can be avoided with early diagnosis and prompt treatment.
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Castleman disease - Diagnosis and treatment - Mayo Clinic
WebJan 24, 2023 · Treatment depends on the type of Castleman disease you have. Unicentric Castleman disease. Unicentric Castleman disease can be cured by surgically removing the diseased lymph node. If the lymph node is in your chest or abdomen — which is often the case — major surgery may be needed.
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Overview of Castleman disease | Blood - American Society of …
WebApr 16, 2020 · Castleman disease (CD) describes a group of at least 4 disorders that share a spectrum of characteristic histopathological features but have a wide range of etiologies, presentations, treatments, and outcomes.
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Castleman Disease - Symptoms, Causes, Treatment | NORD
WebJun 16, 2022 · Castleman disease describes a group of rare disorders with a wide range of symptoms. People with these conditions have enlarged lymph nodes that have a similar appearance when reviewed under the microscope. Castleman disease is first classified based on the number of regions of enlarged lymph nodes that have these abnormal …
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Castleman Disease | Children's Hospital of Philadelphia
WebCastleman disease is a rare immune dysregulation disorder where an overgrowth of cells in your child’s lymph nodes causes them to be enlarged and sometimes also causes fevers or other signs of systemic inflammation (when the immune system is constantly defending the body). Lymph nodes are places where your immune system responds to …
WebOverview & Subtypes. Castleman disease (CD) describes a group of rare disorders that involve enlarged lymph nodes with a similar lymph node appearance under the microscope and a broad range of inflammatory symptoms and laboratory abnormalities. There are four main subtypes of CD: Unicentric Castleman disease (UCD)
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Castleman Disease: Types, Causes, Symptoms, Diagnosis, and …
WebDec 8, 2021 · 7 min read. What Is Castleman Disease? Castleman disease is a rare condition that happens when too many cells grow in your lymph nodes, the small organs that...