cd32b | CD32 - Wikipedia

Keyword	CPC	PCC	Volume	Score	Length of keyword
cd32b	1.82	0.8	6450	76	5

Keyword	CPC	PCC	Volume	Score
cd32b	0.52	0.1	2462	30
cd32b antibody	0.69	0.5	5991	7
cd32b gene	0.99	0.9	4751	79
cd32b expression	1.38	0.1	2716	39
cd32b cd79b	1.42	1	28	15
cd32b reporter assay	0.01	0.2	9902	28
cd32b protein	1.6	0.3	6496	69
cd32b function	0.09	0.9	3271	58
human cd32b antibody flow cytometry	1.12	0.5	3226	90

Search Results related to cd32b on Search Engine

CD32 - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/CD32

WebCD32B. CD32B is an inhibitory surface receptor that is part of a large population of B cell co-receptors, which act to modulate signaling. Activated CD32B has the ability to cross-link with B cell receptors (BCRs), which increases the threshold for B cell activation and downregulates antibody production in the presence of IgG.

DA: 8 PA: 33 MOZ Rank: 75

CD32B, the human inhibitory Fc-γ receptor IIB, as a target for
ashpublications.org

https://ashpublications.org/blood/article/108/7/2384/22468/CD32B-the-human-inhibitory-Fc-receptor-IIB-as-a

WebOct 1, 2006 · Human CD32B (FcγRIIB), the low-affinity inhibitory receptor for IgG, is the predominant Fc receptor (FcR) present on B cells. Immunohistochemical and expression studies have identified CD32B expression in a variety of B-cell malignancies, suggesting that CD32B is a potential immunotherapeutic target for B-cell malignancies.

DA: 46 PA: 31 MOZ Rank: 34

CD32B, the human inhibitory Fc-gamma receptor IIB, as a target …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/16757681/

WebOct 1, 2006 · Abstract. Human CD32B (FcgammaRIIB), the low-affinity inhibitory receptor for IgG, is the predominant Fc receptor (FcR) present on B cells. Immunohistochemical and expression studies have identified CD32B expression in a variety of B-cell malignancies, suggesting that CD32B is a potential immunotherapeutic target for B-cell malignancies.

DA: 60 PA: 87 MOZ Rank: 89

Monoclonal antibodies capable of discriminating the human …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265948/

WebHuman CD32B (FcγRIIB), the low-affinity inhibitory Fcγ receptor (FcγR), is highly homologous in its extracellular domain to CD32A (FcγRIIA), an activating FcγR. Available monoclonal antibodies (mAb) against the extracellular region of …

DA: 13 PA: 39 MOZ Rank: 67

CD19 and CD32b Differentially Regulate Human B Cell …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918864/

WebFeb 2, 2014 · The data indicate that CD19 and CD32b regulate B cell responses differentially, depending on the nature of the B cell stimulus. Although CD32b signals appear critical for modulating activation in response to ligation of BCR, IL-21R, and CD40, CD19 plays a role in regulating TLR-mediated B cell activation.

DA: 44 PA: 100 MOZ Rank: 24

Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891381/

WebFeb 27, 2016 · CD32B is the only inhibitory member of the FcγR family in mice and humans, and binds to monomeric IgG molecules with a low affinity [ 2 ]. It is expressed by B cells and myeloid cells at variable levels depending on the cell subtype and activation state [ 1 ].

DA: 78 PA: 83 MOZ Rank: 44

Development of Anti-CD32b Antibodies with Enhanced Fc Function ... - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/32847974/

WebCD32b expression on malignant B cells is known to provide a mechanism of resistance to rituximab that can be ameliorated with a CD32b-blocking antibody. CD32b, therefore, represents an attractive tumor antigen for targeting with a monoclonal antibody (mAb). To this end, two anti-CD32b mAbs, NVS32b1 and NVS32b2, were developed.

DA: 24 PA: 69 MOZ Rank: 85

Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/25873171/

WebApr 13, 2015 · Here, we demonstrate the therapeutic potential of targeting human (h) FcγRIIB (CD32B), a receptor implicated in immune cell desensitization and tumor cell resistance.

DA: 34 PA: 59 MOZ Rank: 33

FcγRIIb blockage: a promising immunotherapy target for severe …
nature.com

https://www.nature.com/articles/s41392-021-00590-8

WebApr 9, 2021 · It should be noted that earlier studies demonstrate that impeding the Fc γ receptor IIb (FcγRIIb, also known as CD32B) blockade caused higher levels of ISGs in dendritic cells and monocytes ...

DA: 35 PA: 81 MOZ Rank: 100

The accelerating rise of bispecific antibodies outside of oncology
nature.com

https://www.nature.com/articles/d43747-020-00566-7

WebSep 28, 2018 · MGD010 coligates CD32B, a checkpoint molecule, and CD79B to deliver a coinhibitory signal ( Table 1 ). The mechanism of action of MGD010 provides another example of how bispecifics...

DA: 94 PA: 46 MOZ Rank: 92