cftr protein | CFTR - Johns Hopkins Cystic Fibrosis Center

Keyword	CPC	PCC	Volume	Score	Length of keyword
cftr protein	1.84	0.3	8457	57	12
cftr	1.37	0.3	3697	22	4
protein	1.86	0.5	894	70	7

Keyword	CPC	PCC	Volume	Score
cftr protein	1.93	0.1	6633	5
cftr protein function	0.59	0.6	3364	51
cftr protein structure	0.17	0.9	5807	23
cftr protein life cycle	0.53	0.2	8533	89
cftr protein mutation	1.31	1	478	56
cftr protein lies on the sweat glands	1.72	0.3	5500	80
cftr protein lies on the pancreatic duct	1.09	0.4	2169	3
cftr protein lies on the basolateral part	1.64	0.8	3822	8
cftr protein lies on the surface of cilia	1.79	0.4	929	66
cftr protein lies on the lysosomal membrane	1.59	1	6367	69
cftr protein lies on the basolateral side	0.35	0.6	3782	42
cftr protein lies on the basolateral surface	0.77	0.8	3507	46
f508del cftr protein	1.27	0.7	211	31
what does the cftr protein do	0.64	1	7922	18
what is the cftr protein	1.31	0.4	3101	36
how does the cftr protein work	0.68	0.1	9741	69

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CFTR - Johns Hopkins Cystic Fibrosis Center
hopkinscf.org:443

https://hopkinscf.org:443/knowledge/cftr/

WEBThe cystic fibrosis transmembrane conductance regulator (CFTR) is defective in cystic fibrosis (CF). This protein is a channel that sits on the surface of cells and transports chloride and other molecules, such as bicarbonate.

DA: 82 PA: 11 MOZ Rank: 65

Cystic fibrosis transmembrane conductance regulator - Wikipedia
wikipedia.org:443

https://en.wikipedia.org:443/wiki/Cystic_fibrosis_transmembrane_conductance_regulator

WEBCystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the CFTR gene. Geneticist Lap-Chee Tsui and his team identified the CFTR gene in 1989 …

DA: 48 PA: 58 MOZ Rank: 47

Basics of the CFTR Protein | Cystic Fibrosis Foundation
cff.org:443

https://www.cff.org:443/research-clinical-trials/basics-cftr-protein

WEB5 min read. In this article. Summary. The cystic fibrosis transmembrane conductance regulator (CFTR) protein helps to maintain the balance of salt and water on many surfaces in the body, such as the surface of the lung. The CFTR protein is a particular type of protein called an ion channel.

DA: 34 PA: 41 MOZ Rank: 17

CFTR function, pathology and pharmacology at single-molecule …
nature.com:443

https://www.nature.com:443/articles/s41586-023-05854-7

WEBMar 22, 2023 · CFTR belongs to the ATP-binding cassette transporter family of proteins, but uniquely functions as an ion channel 4. It consists of two transmembrane domains that form an ion permeation...

DA: 94 PA: 46 MOZ Rank: 52

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) - Healthline
healthline.com:443

https://www.healthline.com:443/health/cystic-fibrosis/cystic-fibrosis-transmembrane-conductance-regulator

WEBApr 25, 2023 · What Is Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)? Function. CF and CFTR. Effect on lungs. Effect on pancreas. Effect on other systems. CFTR modulators. Genetic testing....

DA: 88 PA: 33 MOZ Rank: 40

The Clinical Biology of Cystic Fibrosis Transmembrane Regulator Protein
nih.gov:443

https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC6414788/

WEBOct 22, 2018 · Abstract. Normal cystic fibrosis (CF) transmembrane regulator (CFTR) protein has multiple functions in health and disease. Many mutations in the CFTR gene produce abnormal or absent protein. CFTR protein dysfunction underlies the classic CF phenotype of progressive pulmonary and GI pathology but may underlie diseases not …

DA: 85 PA: 51 MOZ Rank: 82

CF Genetics: The Basics | Cystic Fibrosis Foundation
cff.org:443

https://www.cff.org:443/intro-cf/cf-genetics-basics

WEBSummary. Cystic fibrosis is caused by mutations in the gene that produces the cystic fibrosis transmembrane conductance regulator (CFTR) protein. In people with CF, mutations in the CFTR gene can disrupt the normal production or functioning of the CFTR protein found in the cells of the lungs and other parts of the body.

DA: 11 PA: 39 MOZ Rank: 13

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR
nih.gov:443

https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC7243099/

WEBApr 22, 2020 · Mutations in the cystic fibrosis transmembrane conductance regulator ( CFTR) gene decrease the structural stability and function of the CFTR protein, resulting in cystic fibrosis.

DA: 54 PA: 23 MOZ Rank: 64

Cystic fibrosis transmembrane conductance regulator (CFTR): …
nih.gov:443

https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC6986785/

WEBAug 28, 2018 · CFTR is unique among human ABC proteins in functioning not as a pump, but as an ion channel. Recent structural data has indicated that CFTR shares broadly similar overall architecture and ATP-dependent conformational changes as …

DA: 83 PA: 94 MOZ Rank: 51

Cystic Fibrosis | New England Journal of Medicine
nejm.org:443

https://www.nejm.org:443/doi/full/10.1056/NEJMra2216474

WEBNov 1, 2023 · CFTR Protein. Cystic fibrosis–causing variants have different implications with respect to CFTR production, processing, expression, and function.

DA: 21 PA: 10 MOZ Rank: 68