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Crithidia is a genus of trypanosomatid Euglenozoa. They are parasites that exclusively parasitise arthropods, mainly insects. They pass from host to host as cysts in infective faeces and typically, the parasites develop in the digestive tracts of insects and interact with the intestinal epithelium using their flagellum.What does Crithidia luciliae stand for?
Crithidia luciliae ( immunofluorescence pattern). Crithidia is a genus of trypanosomatid Euglenozoa. They are parasites that exclusively parasitise arthropods, mainly insects.How does the Crithidia assay detect anti-dsDNA antibodies?
The Crithidia assay detects anti-dsDNA antibodies by their ability to bind to the kinetoplast of C. luciliae, a protozoan organism with a circular dsDNA structure at one pole, and subsequent immunofluorescence. This assay is technically demanding, requiring careful training of technicians to identify...How do autoautoantibodies bind to Crithidia?
Autoantibodies in the test specimen bind to the kinetoplast of Crithidia luciliae, a flagellate parasite which is bound to the slide. The kinetoplast is a complex network of interlocking circular double-stranded DNA (dsDNA) molecules and is the substrate of this test.