WEBApr 3, 2024 · ITGA4 (Integrin Subunit Alpha 4) is a Protein Coding gene. Diseases associated with ITGA4 include Retinitis Pigmentosa 26 and Isolated Macular Dystrophy . Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Integrin Pathway .
WEBITGA4 Info with links in the Cell Migration Gateway Archived 2014-12-11 at the Wayback Machine. Human ITGA4 genome location and ITGA4 gene details page in the UCSC Genome Browser. Overview of all the structural information available in the PDB for UniProt: P13612 (Human Integrin alpha-4) at the PDBe-KB.
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ITGA4 gene methylation status in chronic lymphocytic leukemia
WEBJun 26, 2020 · Methylation status of ITGA4 gene revealed the significance of measuring CpG site 1 as a prognostic marker for CLL and can be a target for therapy. Hypermethylation at certain identified ITGA4 gene CpG sites-1, 2 and 3 is a characteristic feature in CLL. CpG sites-2 and 3 mean methylation levels significantly increased in …
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Reduction of integrin alpha 4 activity through splice modulating
WEBSep 10, 2019 · We describe the development and evaluation of exon skipping AOs designed to induce a non-functional isoform and thereby reduce the activity of integrin alpha 4 protein (ITGA4), also known as...
WEBGene ID: 3676, updated on 10-Mar-2024. Summary. The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that …
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Abnormal promoter DNA hypermethylation of the integrin ... - Nature
WEBJan 26, 2021 · The ITGA4 gene product is a component of two integrins, α4β1 and α4β7, and has been studied in detail to date. Yet, there is still no consensus as to the role integrin α4 plays in tumorigenesis.
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ITGA4 protein expression summary - The Human Protein Atlas