LC-MS – What Is LC-MS, LC-MS Analysis and LC-MS/MS
https://www.technologynetworks.com/analysis/articles/lc-ms-what-is-lc-ms-lc-ms-analysis-and-lc-msms-348238
What Is LC-MS?How Does LC-MS Work?Combining Liquid Chromatography with Tandem Mass SpectrometryLC-MS AnalysisStrengths and Limitations of LC-MSCommon Problems with LC-MSLC separation LC separationLCbrings about a physical separation of the analytes in a liquid sample or a solution of a solid sample. A few microliters of sample solution are injected into a flowing stream of a solvent, called the mobile phase. While the optimal injection volume is dependent on the experimental conditio… LC detectionThe mobile phase flowing out of the column (the eluent) passes through a detector that “responds” to a certain physical or chemical property, such as refractive index or light absorption, of the analytes within it. This response is captured as a signal or a “peak” whose intensity (pea…
LC separationLCbrings about a physical separation of the analytes in a liquid sample or a solution of a solid sample. A few microliters of sample solution are injected into a flowing stream of a solvent, called the mobile phase. While the optimal injection volume is dependent on the experimental conditio…
LC detectionThe mobile phase flowing out of the column (the eluent) passes through a detector that “responds” to a certain physical or chemical property, such as refractive index or light absorption, of the analytes within it. This response is captured as a signal or a “peak” whose intensity (pea…
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