mechanism of action clopidogrel | Clopidogrel: Uses, Interactions, Mec

Keyword	CPC	PCC	Volume	Score	Length of keyword
mechanism of action clopidogrel	1.48	0.5	8608	100	31
mechanism	0.74	1	8139	57	9
of	0.58	0.4	8579	5	2
action	0.85	0.5	2212	16	6
clopidogrel	0.71	0.5	3158	24	11

Keyword	CPC	PCC	Volume	Score
mechanism of action clopidogrel	1.12	0.9	4224	81
clopidogrel mechanism of action simple	1.42	0.6	4353	59
aspirin vs clopidogrel mechanism of action	0.38	0.6	8048	47
clopidogrel plavix mechanism of action	1.62	0.1	7329	63
clopidogrel rxlist mechanism of action	0.96	0.7	7841	13
clopidogrel bisulfate mechanism of action	1.46	0.2	5407	45
clopidogrel mode of action	1.26	0.7	7659	56
clopidogrel 75 mg mechanism of action	1.35	0.2	7439	4
clopidogrel expected pharmacological action	0.2	0.6	496	71
clopidogrel onset of action	1.88	0.6	6144	94
clopidogrel duration of action	1.66	0.1	8293	8
clopidogrel how does it work	0.97	0.1	3402	61
how does clopidogrel work in the body	1.75	0.8	1085	87
clopidogrel mecanismo de accion	1.52	0.7	5264	55
what does the drug clopidogrel do	0.02	0.5	4677	16
what does clopidogrel do	0.54	0.2	4245	54
what does clopidogrel inhibit	0.08	0.2	9171	61
mecanismo de accion de clopidogrel	1.42	0.8	3269	49

Search Results related to mechanism of action clopidogrel on Search Engine

Clopidogrel: Uses, Interactions, Mechanism of Action - DrugBank …
drugbank.com

https://go.drugbank.com/drugs/DB00758

WebMechanism of action Clopidogrel is activated via a 2 steps reaction to an active thiol-containing metabolite. 3 This active form is a platelet inhibitor that irreversibly binds to P2Y 12 ADP receptors on platelets. 9 This binding prevents ADP binding to P2Y 12 receptors, activation of the glycoprotein GPIIb/IIIa complex, and platelet aggregation. 9

DA: 23 PA: 55 MOZ Rank: 13

Clopidogrel - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Clopidogrel

WebMechanism of action. The active metabolite of clopidogrel specifically and irreversibly inhibits the P2Y 12 subtype of ADP receptor, which is important in activation of platelets and eventual cross-linking by the protein fibrin.

DA: 6 PA: 13 MOZ Rank: 9

Clopidogrel: Dosage, Mechanism/Onset of Action, Half-Life
medicine.com

https://www.medicine.com/drug/clopidogrel/hcp

WebFeb 17, 2020 · Mechanism of Action. Clopidogrel requires in vivo biotransformation to an active thiol metabolite. The active metabolite irreversibly blocks the P2Y 12 component of ADP receptors on the platelet surface, which prevents activation of the GPIIb/IIIa receptor complex, thereby reducing platelet aggregation.

DA: 15 PA: 74 MOZ Rank: 5

PLAVIX DESCRIPTION - Food and Drug Administration
fda.gov

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020839s044lbl.pdf

WebMechanism of Action and Pharmacodynamic Properties Clopidogrel is a prodrug, one of whose metabolites is an inhibitor of platelet aggregation. A variety of drugs that inhibit platelet function...

DA: 100 PA: 14 MOZ Rank: 40

Plavix: Package Insert / Prescribing Information - Drugs.com
drugs.com

https://www.drugs.com/pro/plavix.html

Web12.1 Mechanism of Action. Clopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y 12 class of ADP receptors on platelets.

DA: 12 PA: 73 MOZ Rank: 72

HIGHLIGHTS OF PRESCRIBING INFORMATION • Recent …
fda.gov

https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020839s074lbl.pdf

WebPLAVIX ® (clopidogrel ... 12.1 Mechanism of Action 12.2 Pharmacodynamics 12.3 Pharmacokinetics 12.5 Pharmacogenomics 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility 14 CLINICAL STUDIES 14.1 Acute Coronary Syndrome 14.2 Recent Myocardial Infarction, Recent Stroke, or Established

DA: 77 PA: 70 MOZ Rank: 58

Clopidogrel: a review of its mechanism of action. - Europe PMC
europepmc.org

https://europepmc.org/article/MED/16793712

WebJan 1, 1998 · The antiaggregating properties of this compound are well known and, very recently, new results have clarified its mechanism of action. Clopidogrel is active only after intravenous or oral administration, and no circulating activity has been found in the plasma of treated animals or human volunteers.

DA: 1 PA: 40 MOZ Rank: 39

DailyMed - CLOPIDOGREL tablet, film coated
nih.gov

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=be5aae47-c2d3-4576-8588-a4b09fce91b8

WebThe effectiveness of clopidogrel results from its antiplatelet activity, which is dependent on its conversion to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19[see Warnings and Precautions ( 5.1), Clinical Pharmacology ( 12.3)].

DA: 62 PA: 30 MOZ Rank: 93

DailyMed - CLOPIDOGREL tablet
nih.gov

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d176de1d-b1b3-4aa9-b783-d53f65a79e50

WebJan 30, 2024 · The effectiveness of clopidogrel results from its antiplatelet activity, which is dependent on its conversion to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19 [see Warnings and Precautions ( 5.1 ), Clinical Pharmacology ( 12.3)].

DA: 44 PA: 71 MOZ Rank: 45

International Expert Consensus on Switching Platelet …
ahajournals.org

https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.031164

WebFigure 1. Mechanisms of action and binding properties of P2Y 12 inhibitors. Left, Mechanism of action. Activation of the P2Y 12 receptor inhibits adenylyl cyclase, causing a decrease in cAMP and phos-phorylated (P) vasodilator-stimulated phosphoprotein (VASP) levels, and activation of P2Y 12 causes an increase in intracellular

DA: 1 PA: 69 MOZ Rank: 59