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A mutant protein is the protein product encoded by a gene with mutation. Mutated protein can have single amino acid change (minor, but still in many cases significant change leading to disease) or wide-range amino acid changes by e.g. truncation of C-terminus after introducing premature stop codon.
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Mutant Protein - an overview | ScienceDirect Topics
WEBMutations are the result of an expansion of a CAG triplet, encoding polyQ domains of different extent, located in different genes. Except for ataxin2, all these proteins are …
WEBNov 29, 2023 · The p53 protein is a tumour suppressor that plays a crucial role in preventing the formation of cancerous cells. But when it mutates and becomes defective …
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Mutagenesis-based protein structure determination | Nature …
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