13.2A: Disorders in Chromosome Number - Biology LibreTexts
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WEBOct 31, 2023 · Key Points. Aneuploidy is caused by nondisjunction, which occurs when pairs of homologous chromosomes or sister chromatids fail to separate during meiosis. The loss of a single chromosome from a diploid genome is called monosomy (2n-1), while the gain of one chromosome is called trisomy (2n+1).
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