nthl1 gene | NTHL1 Tumor Syndrome - GeneReviews®

Keyword	CPC	PCC	Volume	Score	Length of keyword
nthl1 gene	1.21	0.2	8115	39	10
nthl1	1.55	0.9	7084	97	5
gene	0.63	0.1	6791	34	4

Keyword	CPC	PCC	Volume	Score
nthl1 gene	0.57	0.8	2960	42
nthl1 gene mutation	0.55	0.4	9694	61
nthl1 genereviews	0.03	0.9	1374	57
nthl1 gene mutation carrier	0.16	0.8	4918	95
nthl1 genecards	0.34	0.3	5928	8
nthl1 gene cancer	0.08	0.4	1396	40
nthl1 genetic testing	1.41	0.6	9514	49
nthl1 gene breast cancer	0.61	0.7	374	4
nthl1 gene mutation breast cancer	1.87	1	1913	49
what is gene nthl1	1.01	0.8	5070	37

Search Results related to nthl1 gene on Search Engine

NTHL1 Tumor Syndrome - GeneReviews® - NCBI Bookshelf
nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK555473/

WEBApr 2, 2020 · NTHL1 tumor syndrome is characterized by an increased lifetime risk for colorectal cancer (CRC), breast cancer, and colorectal polyposis. Colorectal polyps can be adenomatous, hyperplastic, and/or sessile serrated. …

DA: 52 PA: 74 MOZ Rank: 44

NTHL1 Gene - GeneCards | NTH Protein | NTH Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=NTHL1

WEBApr 3, 2024 · GeneCards Summary for NTHL1 Gene. NTHL1 (Nth Like DNA Glycosylase 1) is a Protein Coding gene. Diseases associated with NTHL1 include Familial Adenomatous Polyposis 3 and Inherited Cancer-Predisposing Syndrome . Among its related pathways are Packaging Of Telomere Ends and Base excision repair .

DA: 36 PA: 19 MOZ Rank: 12

NTHL1 Tumor Syndrome - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/32239880/

WEBApr 2, 2020 · PMID: 32239880. Bookshelf ID: NBK555473. Excerpt. Clinical characteristics: NTHL1 tumor syndrome is characterized by an increased lifetime risk for colorectal cancer (CRC), breast cancer, and colorectal polyposis. Colorectal polyps can be adenomatous, hyperplastic, and/or sessile serrated. Duodenal polyposis has also been reported.

DA: 86 PA: 98 MOZ Rank: 47

NTHL1 - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/NTHL1

WEBEndonuclease III-like protein 1 is an enzyme that in humans is encoded by the NTHL1 gene. As reviewed by Li et al., NTHL1 is a bifunctional DNA glycosylase that has an associated beta-elimination activity. NTHL1 is usually involved in removing oxidative pyrimidine lesions through base excision repair. NTHL1 catalyses the first step in base ...

DA: 1 PA: 94 MOZ Rank: 7

NTHL1 is a recessive cancer susceptibility gene | Scientific Reports
nature.com

https://www.nature.com/articles/s41598-023-47441-w

WEBNov 30, 2023 · Pathogenic variants in the NTHL1 gene have been determined to cause a recessive multi-tumour syndrome, which is characterized especially by adenomatous polyposis and colorectal cancer (CRC),...

DA: 71 PA: 76 MOZ Rank: 26

NTHL1 is a recessive cancer susceptibility gene - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689455/

WEBNov 30, 2023 · Pathogenic variants in the NTHL1 gene have been determined to cause a recessive multi-tumour syndrome, which is characterized especially by adenomatous polyposis and colorectal cancer (CRC), and with accumulating evidence, BC in …

DA: 56 PA: 32 MOZ Rank: 68

NTHL1 in Genomic Integrity, Aging and Cancer - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748067/

WEBIn this graphical review, we discuss the function of the NTHL1 DNA glycosylase and how genomic mutations and altered function of this protein contributes to cancer and aging. We highlight its role in a rare tumor syndrome, NTHL1-associated polyposis (NAP), and summarize various other polymorphisms in NTHL1 that can induce early hallmarks of ...

DA: 5 PA: 67 MOZ Rank: 86

POLE, POLD1, and NTHL1: the last but not the least hereditary
nature.com

https://www.nature.com/articles/s41388-021-01984-2

WEBAug 6, 2021 · POLE, POLD1, and NTHL1 are involved in DNA replication and have recently been recognized as hereditary cancer-predisposing genes, because their alterations are associated with colorectal cancer...

DA: 61 PA: 34 MOZ Rank: 70

Evaluation of the association of heterozygous germline ... - Nature
nature.com

https://www.nature.com/articles/s41523-021-00255-3

WEBMay 12, 2021 · Bi-allelic loss-of-function (LoF) variants in the base excision repair (BER) gene NTHL1 cause a high-risk hereditary multi-tumor syndrome that includes breast cancer, but the contribution of...

DA: 15 PA: 92 MOZ Rank: 58

Further delineation of the NTHL1 associated syndrome: A report …
wiley.com

https://onlinelibrary.wiley.com/doi/10.1111/cge.13925

WEBBiallelic pathogenic variants in the NTHL1 (Nth like DNA glycosylase 1) gene cause a recently identified autosomal recessive hereditary cancer syndrome predisposing to adenomatous polyposis and colorectal cancer.

DA: 99 PA: 5 MOZ Rank: 63