Sofosbuvir - Wikipedia
https://en.wikipedia.org/wiki/Sofosbuvir
OverviewInteractionsMedical usesContraindicationsSide effectsPharmacologyChemistryHistory Sofosbuvir (in combination with ledipasvir, daclatasvir or simeprevir) should not be used with amiodarone due to the risk of abnormally slow heartbeats. Sofosbuvir is a substrate of P-glycoprotein, a transporter protein that pumps drugs and other substances from intestinal epithelium cells back into the gut. Therefore, inducers of intestinal P-glycoprotein, such as rifampicin and St. John's wort, could reduce the absorption of sofosbuvir. Formula: C₂₂H₂₉FN₃O₉P Trade names: Sovaldi, others Pregnancy category: AU: B1
Formula: C₂₂H₂₉FN₃O₉P
Trade names: Sovaldi, others
Pregnancy category: AU: B1
DA: 94 PA: 30 MOZ Rank: 52