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Basically, a steady state is reached when the rate at which a drug is taken in matches the rate of its elimination. A buildup of the drug does not continue indefinitely because generally the rate at which a drug is eliminated depends on its concentration, so taking more of the drug increases its rate of elimination.What is steady state in pharmacology?
In pharmacokinetics, steady state refers to the situation where the overall intake of a drug is fairly in dynamic equilibrium with its elimination. In practice, it is generally considered that steady state is reached when a time of 4 to 5 times the half-life for a drug after regular dosing is started.How do you calculate half life drugs?
1 Answer. The function calculates the number of half-lifes experienced by the drug by taking the number of days * 24 hours in a day and dividing that by the total number of hours it takes for a half-life of that drug. This is the number of times the drug's dosage would be cut in half.