Rolling back human pluripotent stem cells to an eight-cell
https://pubmed.ncbi.nlm.nih.gov/35314832/
WebMar 22, 2022 · Understanding the process of totipotency in human cells would have broad applications. However, in contrast to in mice 1,2, demonstration of the time of zygotic genome activation or the eight-cell (8C) stage in in vitro cultured human cells has not yet been reported, and the study of embryos is limited by ethical and practical considerations.
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