Afsr.se - Structural and functional characterization of AfsR, an SARP family

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WEBMar 1, 2024 · Streptomyces antibiotic regulatory proteins (SARPs) are widely distributed activators of antibiotic biosynthesis. This study combines cryo-EM structures with biochemical assays to explain how the Streptomyces coelicolor …

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Structural and functional characterization of AfsR, an SARP family
plos.org:443

https://journals.plos.org:443/plosbiology/article?id=10.1371/journal.pbio.3002528

WEBMar 1, 2024 · Streptomyces antibiotic regulatory proteins (SARPs) are widely distributed activators of antibiotic biosynthesis. This study combines cryo-EM structures with biochemical assays to explain how the Streptomyces coelicolor …

DA: 68 PA: 78 MOZ Rank: 66

Streptomyces global regulators AfsR and AfsS interact to …
wiley.com:443

https://enviromicro-journals.onlinelibrary.wiley.com:443/doi/10.1111/1751-7915.14319

WEBNov 20, 2023 · Microbial Biotechnology. RESEARCH ARTICLE. Open Access. Streptomyces global regulators AfsR and AfsS interact to co-regulate antibiotic production and morphological development. Yi Hao, Wenshuai Liu, Xingwang Li, Ying Wen. First published: 20 November 2023. https://doi.org/10.1111/1751-7915.14319.

DA: 79 PA: 25 MOZ Rank: 7

Structural Basis of Streptomyces Antibiotic Regulatory Proteins
researchgate.net:443

https://www.researchgate.net:443/publication/373801265_Structural_Basis_of_Streptomyces_Antibiotic_Regulatory_Proteins_Activating_Transcription

WEBSep 5, 2023 · Sc AfsR, a prominent global regulat or of secondary metabolism, pos sesses a widely 95 distributed SARP domain in all actinomycetes, enabling the acti vation of antibiotic 96 synthesis gene...

DA: 60 PA: 12 MOZ Rank: 70

AfsR as an integrator of signals that are sensed by multiple serine
oup.com:443

https://academic.oup.com:443/jimb/article/30/8/462/5992194

WEBAug 1, 2003 · Protein phosphorylation-dephosphorylation is a key element in cellular mechanisms for the detection, transmission, and integration of intra- and extra-cellular signals in both eukaryotes and prokaryotes.

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AfsR Recruits RNA Polymerase to the afsS Promoter: A Model for
sciencedirect.com:443

https://www.sciencedirect.com:443/science/article/pii/S0022283607003452

WEBJun 1, 2007 · AfsR, a protein belonging to the Streptomyces antibiotic regulatory protein (SARP) family, is a global regulator of secondary metabolism in Streptomyces coelicolor A3 (2). AfsR consists of three major functional domains: an N-terminal SARP domain, a central ATPase domain, and a C-terminal tetratrico peptide repeat (TPR) domain.

DA: 72 PA: 59 MOZ Rank: 51

Structural Basis of Streptomyces Antibiotic Regulatory …
biorxiv.org:443

https://www.biorxiv.org:443/content/10.1101/2023.09.04.556155v1.full.pdf

WEBSep 4, 2023 · 95 ScAfsR, a prominent global regulator of secondary metabolism, possesses a widely 96 distributed SARP domain in all actinomycetes, enabling the activation of antibiotic 97 synthesis gene clusters.

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Streptomyces global regulators AfsR and AfsS interact to co …
researchgate.net:443

https://www.researchgate.net:443/publication/375794083_Streptomyces_global_regulators_AfsR_and_AfsS_interact_to_co-regulate_antibiotic_production_and_morphological_development

WEBNov 20, 2023 · AfsR directly represses ave structural genes ( aveA1 , aveA4 ), cluster‐situated activator gene aveR , and eight key developmental genes, whereas it directly activates afsS , aco (for...

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AfsR is an important regulatory factor for growth and butenyl …
biomedcentral.com:443

https://annalsmicrobiology.biomedcentral.com:443/articles/10.1007/s13213-019-01473-8

WEBApr 26, 2019 · Growth curve and mycelia observation showed that afsR-L overexpression make the stationary phase of S. pogona-AfsR-L longer than that of wild S. pogona by approximate 3 days. Moreover, S. pogona-AfsR-L exhibited a more obvious white phenotype on the solid medium, which means afsR-L overexpression affects the …

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Cross‐talk between two global regulators in Streptomyces: PhoP and AfsR
wiley.com:443

https://onlinelibrary.wiley.com:443/doi/10.1111/j.1365-2958.2009.06624.x

WEBMar 19, 2009 · Free Access. Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription. Fernando Santos-Beneit, Antonio Rodríguez-García, Alberto Sola-Landa, Juan F. Martín. First published: 19 March 2009. https://doi.org/10.1111/j.1365-2958.2009.06624.x. Citations: …

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Primary structure of AfsR, a global regulatory protein for …
sciencedirect.com:443

https://www.sciencedirect.com:443/science/article/pii/037811199090412K

WEBOct 30, 1990 · The afsR gene of Streptomyces coelicolor A3 (2) complements afsB mutations affecting production of pigmented antibiotics. It also directs pigment production in Streptomyces lividans when carried on a plasmid vector. Nucleotide sequencing of the afsR gene revealed that it codes for a 993-amino acid protein ( Mr 105 600) with A- and B …

DA: 6 PA: 19 MOZ Rank: 99

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afsr.se	NS	IN	3600	Target: ns2.forss.net
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Afsr.se - Structural and functional characterization of AfsR, an SARP family

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