Keyword Analysis & Research: citrate metabolite

nih.gov

https://pubmed.ncbi.nlm.nih.gov/24445237/

Citrate is an important substrate in cellular energy metabolism. It is produced in the mitochondria and used in the Krebs cycle or released into cytoplasm through a specific mitochondrial carrier, CIC. In the cytosol, citrate and its derivatives, acetyl-CoA and oxaloacetate, are used in normal and pathological processes. Author: Vito Iacobazzi, Vittoria Infantino Publish Year: 2014

Author: Vito Iacobazzi, Vittoria Infantino

Publish Year: 2014

DA: 39 PA: 29 MOZ Rank: 96

nih.gov

https://pubmed.ncbi.nlm.nih.gov/28058526/

Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS Citrate is key constituent of the tricarboxylic acid (TCA) cycle, serves as substrate for fatty acid and sterol biosynthesis, and functions as a key regulator of intermediary energy metabolism. Author: Niels Westergaard, Helle S Waagepetersen, Bo Belhage, Arne Schousboe Publish Year: 2017

Author: Niels Westergaard, Helle S Waagepetersen, Bo Belhage, Arne Schousboe

Publish Year: 2017

DA: 81 PA: 14 MOZ Rank: 94

nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483798/

Apr 15, 2015 · Stored blood is anticoagulated using citrate (3 g/unit of RBC), which chelates calcium. In a healthy adult, the liver metabolizes 3 g of citrate in 5 min. Infusion rates greater than 1 unit of RBC/5 min, or liver dysfunction, drive citrate elevation and lower plasma ionized calcium [ … Author: Kai Li, Yuan Xu Publish Year: 2015

Author: Kai Li, Yuan Xu

Publish Year: 2015

DA: 74 PA: 70 MOZ Rank: 58

nih.gov

https://pubmed.ncbi.nlm.nih.gov/28073690/

Citrate pathophysiology and metabolism By chelating ionized calcium, citrate allows extracorporeal circuit anticoagulation without a bleeding risk for the patient. Citrate anticoagulation is also associated with a reduced activation of leucocytes and platelets. Citrate clearance by citric acid cycle (Krebs cycle) is not modified by renal … Author: Mehran Monchi Publish Year: 2017

Author: Mehran Monchi

Publish Year: 2017

DA: 10 PA: 5 MOZ Rank: 31

nih.gov

https://pubchem.ncbi.nlm.nih.gov/compound/citrate

Citrate Citrate ion 2-hydroxypropane-1,2,3-tricarboxylate CITRATE ANION UNII-664CCH53PI 664CCH53PI citr 2-Hydroxy-1,2,3-propanetricarboxylate (3-) ANIONSTANDARD-CITRATE 2qpq 3itc 3kgq citrate (3-) citrate (3-) anion 2yg2 3ry8 4eu3 cit (3-) 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ion (3-) BDBM92494 CHEBI:16947 DTXSID30155037 3r69 STL264199 Molecular Formula: C6H5O7-3 PubChem CID: 31348

Molecular Formula: C6H5O7-3

PubChem CID: 31348

DA: 64 PA: 55 MOZ Rank: 5

sciencedirect.com

https://www.sciencedirect.com/topics/medicine-and-dentistry/citrate

Citric acid, 2-hydroxypropane-1,2,3-tricarboxylic acid, is a key metabolic intermediate and is the starting point of the tricarboxylic acid (TCA) cycle. From the viewpoints of production volume and utility, citric acid is one of the most important bioproducts. The annual worldwide output reached approximately 1.6 million ton in 2009.

DA: 67 PA: 88 MOZ Rank: 84

sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S1473050216301999

Feb 01, 2017 · Citrate is metabolized by the Krebs cycle (citric acid cycle), mainly in the liver, but also in muscles and kidneys. Kramer et al. compared the metabolism of citrate in 16 cirrhotic and 16 non-cirrhotic patients [10]. In this study, patients received 0.5 mmol of citrate per kilogram and per hour during 2 h.

DA: 44 PA: 30 MOZ Rank: 6

nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235534/

Jun 19, 2021 · Citrate plays a central role in cancer cells’ metabolism and regulation. Derived from mitochondrial synthesis and/or carboxylation of α-ketoglutarate, it is cleaved by ATP-citrate lyase into acetyl-CoA and oxaloacetate.

DA: 68 PA: 3 MOZ Rank: 62

sciencedirect.com

https://www.sciencedirect.com/topics/neuroscience/citrate

Thus, citrate excretion, which is the difference between its filtration and its reabsorption, with subsequent metabolism that forms HCO 3 –, is functionally equivalent to HCO 3 – excretion. Citrate excretion thereby enables base excretion without altering urine pH, which may be beneficial for minimization of pH-dependent calcium nucleation ...

DA: 4 PA: 96 MOZ Rank: 21

litfl.com

https://litfl.com/citrate-toxicity/

Nov 03, 2020 · CITRATE METABOLISM citrate is metabolised to HCO3 with NADH generation via the Kreb’s cycle metabolism occurs predominately in the liver, kidneys and skeletal muscle RISK FACTORS FOR CITRATE TOXICITY Citrate administration massive transfusion (citrate is used as a preservative) regional citrate anticoagulation for RRT Decreased citrate clearance

DA: 39 PA: 73 MOZ Rank: 37