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There are 335.78 miles from Gainesville to Key Largo in southeast direction and 397 miles (638.91 kilometers) by car, following the Florida's Turnpike route. Gainesville and Key Largo are 6 hours 5 mins far apart, if you drive non-stop. This is the fastest route from Gainesville, FL to Key Largo, FL.How far is Key Largo from Tamarac?
Distance from Tamarac to Key West. Distance between Tamarac and Key West is 240 kilometers (149 miles). Driving distance from Tamarac to Key West is 304 kilometers (189 miles).How far is Key Largo from Coral Gables?
There are 45.27 miles from Coral Gables to Key Largo in southwest direction and 57 miles (91.73 kilometers) by car, following the US-1 route. Coral Gables and Key Largo are 1 hour 4 mins far apart, if you drive non-stop.